Effect of Chromium Supplementation and Exercise on Body Composition, Resting Metabolic Rate and Selected Biochemical Parameters in Moderately Obese Women Following an Exercise Program
Stella L. Volpe, PhD, RD, Hui-Wen Huang, MS, Kanokwan Larpadisorn, MS, and Ingrid I. Lesser, Lic
Department of Nutrition, University of Massachusetts, Amherst, Massachusetts (S.L.V., H.-W.H., K.L.), Faculty of Medicine, School of Nutrition, Univeristy of Buenos Aires, Buenos Aires, ARGENTINA (I.I.L.) [firstname.lastname@example.org]
Objective: To investigate the effect of chromium picolinate (CP) supplementation on body composition, resting metabolic rate (RMR), selected biochemical parameters and iron and zinc status in moderately obese women participating in a 12-week exercise program.
Methods: Forty-four women, 27 to 51 years of age, were randomly assigned to two groups based on their body mass index. Subjects received either 400 g/day of chromium as a CP supplement or a placebo in double-blind fashion and participated in a supervised weight-training and walking program two days per week for 12 weeks. Body composition and RMR were measured at baseline, 6 and 12 weeks. Selected biochemical parameters and iron and zinc status were measured at baseline and 12 weeks.
Results: Body composition and RMR were not significantly changed by CP supplementation. No significant differences in fasting plasma glucose, serum insulin, plasma glucagon, serum C-peptide and serum lipid concentrations or in iron and zinc indices were found between the two groups over time. Serum total cholesterol concentration significantly decreased (p = 0.0016) over time for all subjects combined, probably as a result of the exercise training. Exercise training significantly reduced total iron binding capacity (TIBC) by 3% for all subjects combined (p = 0.0011).
Conclusions: Twelve weeks of 400 g/day of chromium as a CP supplement did not significantly affect body composition, RMR, plasma glucose, serum insulin, plasma glucagon, serum C-peptide and serum lipid concentrations or iron and zinc indices in moderately obese women placed on an exercise program. The changes in serum total cholesterol levels and TIBC were a result of the exercise program.